CBS Sports has released its Week 8 NFL picks, predictions, and best bets for every matchup. With four teams on bye (New Orleans, New York Giants, San Francisco, Houston), the slate features several intriguing betting angles. Below are the highlighted games with projected scores and recommended picks.
Indianapolis Colts at Jacksonville Jaguars
The Colts (2-5) travel to face the Jaguars (4-2) coming off a bye. Indianapolis has struggled offensively, averaging 4.5 yards per play (tied for worst in the NFL). Quarterback Daniel Jones ranks 31st in passer rating and has thrown an interception in all but one game this season. Jacksonville's pass defense allows an 87.7 passer rating and has seven interceptions (tied for third-most). Trevor Lawrence is playing at an MVP level. Projected score: Jaguars 33, Colts 20. Pick: Jaguars -10.
Tennessee Titans at Cincinnati Bengals
The Bengals showed explosive potential in a 35-point second-half comeback against Baltimore. Tennessee traded defensive tackle Jeffery Simmons to Chicago this week, weakening their defense. The Titans rank 29th in passer rating and last in yards per attempt, while Cincinnati's defense holds opponents to a 35% red-zone touchdown rate (third-best). Projected score: Bengals 35, Titans 21. Pick: Bengals -12.5.
Los Angeles Chargers at Los Angeles Rams
Despite the Chargers' bye week, Justin Herbert has a league-high 5.6% turnover-worthy throw rate. The Rams allow only 186.3 passing yards per game (fourth-lowest) and have five interceptions. Los Angeles' run defense yields 123.8 yards per game, setting up a big day for Rams backs Kyren Williams and Blake Corum. Projected score: Rams 30, Chargers 17. Pick: Rams -6.5.
New England Patriots at Miami Dolphins
New England is 8-4-1 against the spread on the road under Mike Vrabel and 3-2 ATS as a road favorite with a 13-point average margin. The Patriots have a rest advantage after playing Thursday. Miami allows 5.7 yards per play and a league-high 116.8 passer rating against. Drake Maye should exploit the Dolphins' secondary. Projected score: Patriots 30, Dolphins 20. Pick: Patriots -7.
Philadelphia Eagles at Washington Commanders
Philadelphia plays on a short week after Monday night, while Washington is rested off a bye. The Commanders lost top receiver Terry McLaurin for the season, but Stefon Diggs, rookie Antonio Williams, and tight end Chig Okonkwo can step up. Eagles running back Saquon Barkley is hampered by a hamstring injury. Philadelphia is 0-2 ATS on the road with an -8.0 average margin. Projected score: Commanders 27, Eagles 17. Pick: Commanders -6.
Remaining Week 8 Picks
Cardinals at Cowboys: Projected Cowboys 28, Cardinals 23. Pick: Cardinals +7. Falcons at Buccaneers: Projected Falcons 24, Buccaneers 20. Pick: Falcons +2.5. Ravens at Bills: Projected Bills 30, Ravens 28. Pick: Ravens +3. Browns at Steelers: Projected Steelers 26, Browns 20. Pick: Steelers -3.5. Raiders at Jets: Projected Raiders 24, Jets 21. Pick: Raiders +1.5. Vikings at Lions: Projected Lions 27, Vikings 21. Pick: Lions -3. Chiefs at Broncos: Projected Chiefs 23, Broncos 20. Pick: Chiefs -1.5. Bears at Seahawks (Monday): Projected Seahawks 27, Bears 23. Pick: Seahawks -3.



