The opening betting odds for the upcoming NFL matchup between the Indianapolis Colts and the Dallas Cowboys show a significant shift against the Colts, according to early lines released by sportsbooks.
The Colts, who have struggled in recent weeks, are seeing their odds worsen as the game approaches. The Dallas Cowboys, coming off a game against the Philadelphia Eagles on October 26, 2026, are favored in the early betting market.
Oddsmakers have adjusted the point spread and moneyline in favor of Dallas, reflecting the Colts' recent performance decline. Further line movement is expected as more betting action comes in before kickoff.
