The Jacksonville Jaguars aim for their fifth win in six games when they face the Baltimore Ravens on Thursday Night Football. Kickoff is set for 8:15 p.m. ET at M&T Bank Stadium in Baltimore.
Jacksonville (5-2) leads the AFC South and is 4-2 in conference play, coming off a 42-7 victory over the Indianapolis Colts. Baltimore (4-4) sits fourth in the AFC North at 2-3 in conference games after a 36-10 loss at Buffalo.
The Ravens will be without their top two quarterbacks, Lamar Jackson (thumb) and Tyler Huntley (toe), leaving undrafted rookie Joe Fagnano to start. Fagnano completed 10 of 21 passes for 91 yards with one interception in relief against the Bills.
The Jaguars are 10-point favorites, marking the largest road favorite of the 2026 NFL season. The over/under is 39.5 points. Jacksonville is 4-3 against the spread this season, while Baltimore is 2-5-1.
Veteran sportswriter Mike Tierney, who has covered the NFL for decades and reported from seven Super Bowls, enters the matchup on a 32-14-1 run on Ravens-involved picks, returning $1,627 per $100 wagered. Tierney leans toward the under 39.5, noting the under has hit in six of the last nine meetings since 2008 and in six of Jacksonville's last 10 games.
With Jackson and Huntley sidelined, Baltimore's offense ranks 15th in scoring at 22.4 points per game but faces a Jaguars defense allowing the second-fewest points in the league at 15.9 per game. Tierney has identified a key X-factor that makes one side of the spread a strong play.
