The 6-1 Minnesota Vikings host the 6-1 Buffalo Bills on Monday Night Football after suffering their first loss of the season last Sunday against the Detroit Lions. With quarterback Kyler Murray nursing a week-to-week hamstring injury, Carson Wentz is set to make his second start of the season. The Vikings' offense, which has struggled at times under Murray, may see a boost from Wentz's familiarity with coach Kevin O'Connell's system.
Four bold predictions for the matchup include: Carson Wentz throwing for his first 300-yard game of the season against a bottom-tier Bills passing defense; star receiver Justin Jefferson recording a season-high 150 yards and two touchdowns as Wentz looks to feed him early and often; the Vikings' defense, coordinated by Brian Flores, holding NFL rushing leader James Cook to fewer than 75 yards after allowing 230 rushing yards to Detroit and 154 to Jonathan Taylor the week prior; and the Vikings pulling off an upset by beating the Bills by 10 or more points, leveraging their trusted defense and special teams alongside an improved offensive performance.
