San Francisco 49ers running back Christian McCaffrey was absent from practice on Wednesday, November 4, 2026, according to a report from USA TODAY Sports. The All-Pro running back's absence raises questions about his availability for the team's upcoming game.
McCaffrey, who has been a cornerstone of the 49ers' offense since his acquisition, has dealt with various injuries throughout his career. The team has not yet released an official injury report detailing the reason for his missed session.
Head coach Kyle Shanahan is expected to address McCaffrey's status later in the week as the 49ers prepare for their next opponent. The running back's participation in Thursday and Friday practices will be a key indicator of his potential availability for Sunday's game.



