The Minnesota Vikings aim to rebound from their first loss of the season when they host the Buffalo Bills on Monday Night Football at U.S. Bank Stadium. Kickoff is set for 8:15 p.m. ET.
Minnesota fell 19-15 at Detroit last week but remains undefeated at home. Buffalo sits atop the AFC East after a 36-10 victory over the Baltimore Ravens. The Vikings lead the all-time series 9-6, including a 33-30 overtime win in the most recent meeting in 2022.
Vikings quarterback Kyler Murray has been ruled out with a hamstring injury, placing Carson Wentz under center. The Bills enter as 3.5-point favorites with an over/under of 45.5 points.
Expert Analysis
SportsLine's R.J. White, who has posted an 803-705-41 against-the-spread record from 2017-25 and returned over $2,700 per $100 wagered, enters the game on a 39-17-3 run on Vikings picks, yielding more than $2,200 per $100. White is leaning toward the under 45.5 total points.
"The Vikings offense is coming off two uninspiring efforts against questionable defenses, and the unit has managed just six offensive touchdowns since Week 2," White said. He notes Minnesota's defense allows a league-low 13.3 points per game and that the Vikings have gone under the total in nine of their last ten games.
White has also identified a key X-factor that makes one side of the spread a strong play, though the specific detail is available through his full analysis.
